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Coronavirus

The challenge of conducting clinical research during a pandemic

Drug treatments and vaccines for Covid-19 are needed fast. But developing them in mid-outbreak is logistically hard and ethically tricky. A veteran vaccine researcher explains.

How we make decisions during a pandemic

From mask wearing to physical distancing, individuals wield a lot of power in how the coronavirus outbreak plays out. Behavioral experts reveal what might be prompting people to act — or not.

The time of trials: Waiting for a coronavirus vaccine

An infected and impatient world needs protection from Covid-19, but rushing it won't be easy. How can we speed up a complicated process?

Data viz experts explain Covid-19 graphics | Things to Know

VIDEO: Scientists break down what some popular visualizations of the pandemic can and cannot tell us

Building a mouse squad against Covid-19

It began with an email from Wuhan, a Maine laboratory and mouse sperm from Iowa. Now that lab is on the verge of supplying a much-needed animal for SARS-CoV-2 research.

Loss of smell, confusion, strokes: Does Covid-19 target the nervous system?

Reports of patients with neurological symptoms have emerged during the pandemic. Scientists don’t yet know whether these are a direct effect of the virus or part of the body’s response to infection.

Keys to coping with lockdown

Studies on astronauts and Antarctic crews reveal how extreme confinement affects small groups. Scientists are racing to figure out isolation’s impact on the rest of us.

Covid-19 antibody testing: Tougher than true/false

Antibodies should indicate if someone has had an infection in the past. But the promise of “immunity testing” is plagued by uncertainty about how the immune system responds to the coronavirus, as well as concerns about the tests’ accuracy.

Could Covid-19 usher in a new era of working from home?

Millions of people have been forced to work remotely — but experts say the practice won’t necessarily stick

How disease sleuths are using genomics to track the coronavirus

Rapid sequencing of viral genomes can help public health officials figure out the origins, spread and nature of quickly moving epidemics

Infectious disease: Making — and breaking — the animal connection

We know pathogens from other species can endanger us. Scientists are better equipped than ever to do something about it, but political buy-in is crucial.

What is a cytokine storm?

An immune reaction gone wild seems to be linked with the most severe cases of pandemic Covid-19. Here’s what happens.

An old problem: How immune responses weaken with age

The body’s defenses lose flexibility and diversity over time, and protective responses to vaccines weaken as well. Scientists are working on ways to boost seniors’ protections against influenza, the novel coronavirus and other pathogens.

Digital disease surveillance: Tracking a pandemic

Social media posts and online searches may offer vital clues about the spread of influenza — and now Covid-19. But they also risk errors and threaten privacy.

Closing in on the new coronavirus

The eye-catching spikes sticking out from the surface of SARS-CoV-2 may inspire new ways to prevent or treat Covid-19 infections