With the first medical therapy approved and systems like CRISPR-Cas showing up in complex cells, there’s a lot going on in the genome editing field. Here’s our primer.
OPINION: A massive bias in medical studies toward men of European origin means that genetic variants in understudied populations don’t get the focus they deserve
Polygenic risk scores — a patient’s chance, based on tiny DNA variants, of developing cardiovascular disease, breast cancer and more — are coming to clinics. But there are kinks to iron out and accuracy remains an issue.
They have held our fascination ever since we first identified their remains. Today, thanks to new artifacts and technologies, findings about our closest relatives are coming thick and fast.
After turning up hundreds of genes with hard-to-predict effects, some scientists are now probing the grander developmental processes that shape face geometry
A scientist whose work was key to identifying, studying and finding treatments for this life-threatening virus discusses the scientific journey and challenges that persist
Scientists agree that eons ago, a bacterium took up residence inside another cell and became its powerhouse, the mitochondrion. But there are competing theories about the birth of other organelles such as the nucleus and endoplasmic reticulum.
Their genital anatomy, musculature and aggressiveness have made them a model for studying the phenomenon of female masculinization — and demonstrate that sometimes, it’s not easy to tell the difference between male and female
As cells divide, they must copy all of their chromosomes once and only once, or chaos would ensue. How do they do it? Key controls happen well before replication even starts.
Genetic conditions like Dravet syndrome, which causes severe childhood epilepsy, are hard to tackle with traditional gene therapy. New approaches in the works include using antisense therapy to boost mRNA splicing.
Paleogenomic research has expanded rapidly over the past two decades, igniting heated debate about handling remains. Who gives consent for study participants long gone — and who should speak for them today?
The way we see and describe hues varies widely for many reasons: from our individual eye structure, to how our brain processes images, to what language we speak, or even if we live near a body of water
Differences between the immune systems of males and females — in particular, ones involving cells called microglia — might help explain why the risk for conditions such as autism and Alzheimer’s varies between the sexes
The world’s natural history collections hold billions of biological specimens, many of which still contain DNA. Scientists exploring these genetic repositories are gaining new, historical perspectives on how animals evolve.
Carminic acid is a bright, natural coloring used in some cosmetics and foods. It’s traditionally sourced from ‘farming’ an insect on acres of prickly pears. Today, scientists are moving to engineer it in microbes.
Plants and animals are evolving in cities around the world — offering ways to study longstanding scientific questions and clues to where climate change is taking us
Carnivorous plants fascinate as much now as when their gruesome diet was first discovered. Molecular biology is helping botanists trace the origins of their predatory ways.
PODCAST: The journey to solving the structures of these critically important molecules began with a chance discovery. Today, after decades of painstaking lab work and huge technological leaps, the field of protein science is exploding. (Season 2/Episode 3)
Suddenly, biologists have hundreds of complete genome sequences of our feathered friends. That wealth of data is revolutionizing understanding of bird biology and evolution.
Is Chernobyl a radioactive wasteland reeling from chronic radiation, or a post-nuclear paradise with thriving populations of animals and other life forms? Studies don’t always agree about levels of mutations and other ill effects.
Some lizard species do without males altogether. Scientists are studying these all-female species to see what they might reveal about the pros and cons of sex.
COMIC: As it spreads throughout the world, the virus that causes Covid-19 has been changing. Scientists are tracking those changes, hoping to stay one step ahead of worrisome strains.
Pathogens can make us sick. Just how sick depends on genetic variations, including ones that sabotage immune molecules called interferons. A better understanding could lead to new treatments for Covid-19 and other scourges.
Genes, microbes and other factors govern how each person’s body processes nutrients. Understanding the connections could help optimize diets — and health.
Only recently have scientists directly witnessed this most pivotal of events in biology, thanks to new technology that allows them to observe the process in living cells. It’s teaching them a lot.
Only about 10 percent of people with breast cancer have links to known gene variants, but another 20 percent have significant family history. Scientists are delving deeper into the genome to find what remains unexplained.
Despite numerous studies and 30-plus genomes under their belts, scientists are still struggling to nail down the defining traits of these tall, long-lived, woody plants
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